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The neuro-ophthalmological manifestations of NMOSD and MOGAD—a comprehensive review

The neuro-ophthalmological manifestations of NMOSD and MOGAD—a comprehensive review

Journal: Eye; March 16, 2023

Author(s): Negar Moheb, John J. Chen

Features of optic neuritis and associated clinical signs in NMOSD and MOGAD

Optic neuritis is a common occurrence that can lead to vision loss in multiple sclerosis, NMOSD, and MOGAD. The features of optic neuritis are well described for multiple sclerosis but not for NMOSD and MOGAD. These diseases differ in severity, rate of recurrence, and overall outcomes, which is why prompt and accurate diagnosis and management is essential. This review article summarizes the characteristic neuro-ophthalmological signs in NMOSD and MOGAD, serum biomarkers and MRI findings, as well as immediate relapse management and long-term therapies used for NMOSD and MOGAD.

Related article: Optic neuritis — different forms, treatments, diagnosis, and prognosis

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